About CP-101

CP-101 embodies the fusion of "Science" and "Philosophy." Since the establishment of Iwade Mycological Research Institute in 1963, we have accumulated over 45 years of scientific research, consistently dedicated to "supporting healthy living through the power of science." Through deep collaboration with Japan's top universities, we transform advanced research findings into exceptional health products, contributing to the healthy lives of consumers worldwide.

  • Our Mission

    To support healthy living through the power of science, providing exceptional quality health products to consumers worldwide, making scientific research benefits accessible to everyone who pursues health.

  • Our Vision

    To become a leading health technology brand in Asia and globally, enabling more people to enjoy the health benefits brought by science and creating a better quality of life.

  • Science-Based

    Always grounded in rigorous scientific research for product development. Our research is conducted with reference to the research field of Professor Tasuku Honjo, the 2018 Nobel Prize laureate.

  • Global Perspective

    CP-101 brand has expanded operations to Japan, China, Southeast Asia, and multiple other regions, contributing to healthy living worldwide.

Brand History

  • 1963 · The Beginning

    Iwade Mycological Research Institute was established, successfully cultivating the "Iwade 101 Strain" of Agaricus blazei, laying the scientific foundation for Agaricus research. This breakthrough achievement initiated decades of systematic research.

  • 1980s · International Collaboration

    Established deep collaborative relationships with Mie University in Japan, as well as research institutions in Europe and the United States. Continuously optimized extraction technologies, conducted multiple clinical studies, and accumulated rich scientific validation data.

  • Patent Technology Breakthrough

    Successfully developed subcritical water extraction technology (Patent No. 7141630), breaking through the limitations of traditional high-temperature extraction. This technology achieves efficient extraction while preserving active ingredients.

  • Present · Continuous Innovation

    Over 45 years of research accumulation, holding multiple core patents including subcritical water extraction (7141630), Tie2 pathway (6246859), and Livinol™ (5980228). Products are now distributed worldwide.

Core Patent Technologies

Subcritical Water Extraction

Patent No. 7141630. Using low-temperature, low-pressure process to efficiently extract β-glucan and other active components, avoiding quality degradation from traditional high-temperature extraction.

Tie2 Pathway Technology

Patent No. 6246859. Helps maintain healthy vascular conditions and smooth blood circulation, supporting efficient nutrient transport.

Livinol™ Patented Ingredient

Patent No. 5980228. High-concentration Garcinol extracted from Garcinia, supporting metabolic health and cellular vitality.

Enteric Sustained-Release Technology

Advanced pH-responsive enteric coating that resists gastric acid erosion, precisely releasing active ingredients in the intestine for improved bioavailability.

Quality Certifications

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GMP Certified Production

All products are manufactured in Japanese GMP certified facilities, strictly adhering to pharmaceutical-grade production standards.

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ISO International Standards

Compliant with ISO international quality management system standards, from raw materials to finished products following international standards.

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FDA Facility Registration

Production facilities have passed U.S. FDA registration certification, allowing products to legally enter the North American market.

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SGS Third-Party Testing

Every batch is tested by internationally authoritative organizations like SGS, with transparent and accessible quality reports.

Product Series

R&D Strength

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45+ Years of Research

Since 1963, continuous systematic research on Agaricus blazei and health components.

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3+ Core Patents

Holding multiple core patent technologies including subcritical water extraction, Tie2 pathway, and Livinol™.

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2+ Top University Partners

Long-term research partnerships with top institutions including Mie University and Nagoya University.

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100% Japanese Quality

Premium Japanese domestic raw materials, GMP certified factory production, full traceability.

Research Collaborators

  • Professor Gabazza Esteban

    Special Professor, Graduate School of Medicine, Mie University. Specializing in immunology and respiratory internal medicine, with many years of research experience. Professor Gabazza's research focuses on immune system regulatory mechanisms, providing important scientific basis for the immune support functions of CP-101 series products.

  • Dr. Kunihiko Okada

    Doctor of Medicine (Nagoya University). With many years of research experience in regenerative medicine, Dr. Okada has made significant contributions to stem cell cultivation, bone regeneration, and tissue engineering research, serving as the core R&D consultant for the Stem Cell Supernatant Series products.

Partner Institutions

  • Mie University

    Mie National University is a renowned research institution in the fields of medicine and immunology. The university participated in specific research on Agaricus blazei and verified functional components and advanced extraction technologies. Professor Gabazza Esteban from the Graduate School of Medicine is our core research collaborator.

  • Iwade Mycological Research Institute

    Founded in 1963, this is the research institute that successfully cultivated the "Iwade 101 Strain" of Agaricus blazei, which is also the origin of the CP-101 brand name. Over 60 years of professional research accumulation has made it the authoritative institution in global Agaricus research.